Genomic and transcriptomic insights into the thermo-regulated biosynthesis of validamycin in <it>Streptomyces hygroscopicus</it> 5008

<p>Abstract</p> <p>Background</p> <p><it>Streptomyces hygroscopicus</it> 5008 has been used for the production of the antifungal validamycin/jinggangmycin for more than 40 years. A high yield of validamycin is achieved by culturing the strain at 37°C, rather...

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Bibliographic Details
Main Authors: Wu Hang, Qu Shuang, Lu Chenyang, Zheng Huajun, Zhou Xiufen, Bai Linquan, Deng Zixin
Format: Article
Language:English
Published: BMC 2012-07-01
Series:BMC Genomics
Subjects:
Online Access:http://www.biomedcentral.com/1471-2164/13/337