HEMD: an integrated tool of human epigenetic enzymes and chemical modulators for therapeutics.

BACKGROUND: Epigenetic mechanisms mainly include DNA methylation, post-translational modifications of histones, chromatin remodeling and non-coding RNAs. All of these processes are mediated and controlled by enzymes. Abnormalities of the enzymes are involved in a variety of complex human diseases. R...

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Bibliographic Details
Main Authors: Zhimin Huang, Haiming Jiang, Xinyi Liu, Yingyi Chen, Jiemin Wong, Qi Wang, Wenkang Huang, Ting Shi, Jian Zhang
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3382562?pdf=render