Modulation of NCAM/FGFR1 signaling suppresses EMT program in human proximal tubular epithelial cells.

Neural cell adhesion molecule (NCAM) and fibroblast growth factor receptor 1 (FGFR1) cross-talk have been involved in epithelial-to-mesenchymal transition (EMT) process during carcinogenesis. Since EMT also contributes to maladaptive repair and parenchymal damage during renal fibrosis, we became enc...

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Bibliographic Details
Main Authors: Maja Životić, Björn Tampe, Gerhard Müller, Claudia Müller, Aleksandar Lipkovski, Xingbo Xu, Gunsmaa Nyamsuren, Michael Zeisberg, Jasmina Marković-Lipkovski
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2018-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC6211750?pdf=render