A Local Counter-Regulatory Motif Modulates the Global Phase of Hormonal Oscillations
Abstract Counter-regulatory elements maintain dynamic equilibrium ubiquitously in living systems. The most prominent example, which is critical to mammalian survival, is that of pancreatic α and β cells producing glucagon and insulin for glucose homeostasis. These cells are not found in a single gla...
Main Authors: | , , , , |
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Format: | Article |
Language: | English |
Published: |
Nature Publishing Group
2017-05-01
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Series: | Scientific Reports |
Online Access: | https://doi.org/10.1038/s41598-017-01806-0 |