Inhibition of constitutively active Jak-Stat pathway suppresses cell growth of human T-cell leukemia virus type 1-infected T-cell lines and primary adult T-cell leukemia cells

Inhibition of constitutively active Jak-Stat pathway suppresses cell growth of human T-cell leukemia virus type 1-infected T-cell lines and primary adult T-cell leukemia cells

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<p>Abstract</p> <p>Background</p> <p>Human T-cell leukemia virus type 1 (HTLV-1), the etiologic agent for adult T-cell leukemia (ATL), induces cytokine-independent proliferation of T-cells, associated with the acquisition of constitutive activation of Janus kinases (Jak...

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Bibliographic Details
Main Authors: Matsuda Takehiro, Masuda Masato, Okudaira Taeko, Uchihara Jun-nosuke, Kawakami Hirochika, Tomita Mariko, Tanaka Yuetsu, Ohshiro Kazuiku, Mori Naoki
Format: Article
Language:English
Published: BMC 2006-04-01
Series:Retrovirology
Online Access:http://www.retrovirology.com/content/3/1/22

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http://www.retrovirology.com/content/3/1/22

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