PHF20 Promotes Glioblastoma Cell Malignancies Through a WISP1/BGN-Dependent Pathway

PHF20 Promotes Glioblastoma Cell Malignancies Through a WISP1/BGN-Dependent Pathway

Glioblastoma (GBM) stem cells are resistant to cancer therapy, and therefore responsible for tumor progression and recurrence after conventional therapy. However, the molecular mechanisms driving the maintenance of stemness and dedifferentiation are poorly understood. In this study, we identified pl...

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Bibliographic Details
Main Authors: Qianquan Ma, Wenyong Long, Changsheng Xing, Chongming Jiang, Jun Su, Helen Y. Wang, Qing Liu, Rong-Fu Wang
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-10-01
Series:Frontiers in Oncology
Subjects:
PHF20
glioblastoma
WISP1
BGN
cancer stem cell-like traits
epigenetic regulation
Online Access:https://www.frontiersin.org/article/10.3389/fonc.2020.573318/full

Internet

https://www.frontiersin.org/article/10.3389/fonc.2020.573318/full

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