Clinical and genetic differences between bipolar disorder type 1 and 2 in multiplex families

Abstract The two major subtypes of bipolar disorder (BD), BD-I and BD-II, are distinguished based on the presence of manic or hypomanic episodes. Historically, BD-II was perceived as a less severe form of BD-I. Recent research has challenged this concept of a severity continuum. Studies in large sam...

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Bibliographic Details
Main Authors: Jose Guzman-Parra, Fabian Streit, Andreas J. Forstner, Jana Strohmaier, Maria José González, Susana Gil Flores, Francisco J. Cabaleiro Fabeiro, Francisco del Río Noriega, Fermin Perez Perez, Jesus Haro González, Guillermo Orozco Diaz, Yolanda de Diego-Otero, Berta Moreno-Kustner, Georg Auburger, Franziska Degenhardt, Stefanie Heilmann-Heimbach, Stefan Herms, Per Hoffmann, Josef Frank, Jerome C. Foo, Lea Sirignano, Stephanie H. Witt, Sven Cichon, Fabio Rivas, Fermín Mayoral, Markus M. Nöthen, Till F. M. Andlauer, Marcella Rietschel
Format: Article
Language:English
Published: Nature Publishing Group 2021-01-01
Series:Translational Psychiatry
Online Access:https://doi.org/10.1038/s41398-020-01146-0