Antinociceptive effects of morphine and naloxone in mu-opioid receptor knockout mice transfected with the MORS196A gene

<p>Abstract</p> <p>Background</p> <p>Opioid analgesics such as morphine and meperidine have been used to control moderate to severe pain for many years. However, these opioids have many side effects, including the development of tolerance and dependence after long-term...

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Bibliographic Details
Main Authors: Tao Pao-Luh, Lu Ru-Band, Han Jun-Ming, Ma Hsin-I, Chen Shiou-Lan, Law Ping-Yee, Loh Horace H
Format: Article
Language:English
Published: BMC 2010-04-01
Series:Journal of Biomedical Science
Online Access:http://www.jbiomedsci.com/content/17/1/28