Engineered Biomimetic Platelet Membrane-Coated Nanoparticles Block Staphylococcus aureus Cytotoxicity and Protect Against Lethal Systemic Infection

Engineered Biomimetic Platelet Membrane-Coated Nanoparticles Block Staphylococcus aureus Cytotoxicity and Protect Against Lethal Systemic Infection

Staphylococcus aureus (S. aureus) is a leading human pathogen capable of producing severe invasive infections such as bacteremia, sepsis, and endocarditis with high morbidity and mortality, exacerbated by the increasingly widespread antibiotic resistance exemplified by methicillin-resistant strains...

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Bibliographic Details
Main Authors: Jwa-Kyung Kim, Satoshi Uchiyama, Hua Gong, Alexandra Stream, Liangfang Zhang, Victor Nizet
Format: Article
Language:English
Published: Elsevier 2021-08-01
Series:Engineering
Subjects:
Nanoparticle
Nanosponge
Platelet
Staphylococcus aureus
Bacterial toxins
Sepsis
Online Access:http://www.sciencedirect.com/science/article/pii/S2095809920303313

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http://www.sciencedirect.com/science/article/pii/S2095809920303313

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