Novel triazine JPC-2067-B inhibits Toxoplasma gondii in vitro and in vivo.

Novel triazine JPC-2067-B inhibits Toxoplasma gondii in vitro and in vivo.

Toxoplasma gondii causes substantial morbidity, mortality, and costs for healthcare in the developed and developing world. Current medicines are not well tolerated and cause hypersensitivity reactions. The dihydrotriazine JPC-2067-B (4, 6-diamino-1, 2-dihydro-2, 2-dimethyl-1-(3'(2-chloro-, 4-tr...

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Bibliographic Details
Main Authors: Ernest J Mui, Guy A Schiehser, Wilbur K Milhous, Honghue Hsu, Craig W Roberts, Michael Kirisits, Stephen Muench, David Rice, J P Dubey, Joseph W Fowble, Pradipsinh K Rathod, Sherry F Queener, Susan R Liu, David P Jacobus, Rima McLeod
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2008-03-01
Series:PLoS Neglected Tropical Diseases
Online Access:http://europepmc.org/articles/PMC2254147?pdf=render

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http://europepmc.org/articles/PMC2254147?pdf=render

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