Hydrophobicity of Residue 128 of the Stress-Inducible Sigma Factor RpoS Is Critical for Its Activity

Hydrophobicity of Residue 128 of the Stress-Inducible Sigma Factor RpoS Is Critical for Its Activity

RpoS is a key stress-inducible sigma factor that regulates stress resistance genes in Escherichia coli, such as the katE gene encoding catalase HPII and the glg genes encoding glycogen synthesis proteins. Monitoring RpoS activity can provide information on the stress sensitivity of E. coli isolates...

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Bibliographic Details
Main Authors: Tadayuki Iwase, Takashi Matsuo, Saiko Nishioka, Akiko Tajima, Yoshimitsu Mizunoe
Format: Article
Language:English
Published: Frontiers Media S.A. 2017-04-01
Series:Frontiers in Microbiology
Subjects:
RpoS
missense mutation
stress response
Shiga toxin-producing E. coli (STEC)
clinical isolates
food-borne pathogens
Online Access:http://journal.frontiersin.org/article/10.3389/fmicb.2017.00656/full

Internet

http://journal.frontiersin.org/article/10.3389/fmicb.2017.00656/full

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