Interleukin-1 receptor antagonist is beneficial after subarachnoid haemorrhage in rat by blocking haem-driven inflammatory pathology

SUMMARY Subarachnoid haemorrhage (SAH) is a major contributor to the burden of stroke on society. Treatment options are limited and animal models of SAH do not always mimic key pathophysiological hallmarks of the disease, thus hindering development of new therapeutics. Inflammation is strongly assoc...

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Bibliographic Details
Main Authors: Andrew D. Greenhalgh, David Brough, Emily M. Robinson, Sylvie Girard, Nancy J. Rothwell, Stuart M. Allan
Format: Article
Language:English
Published: The Company of Biologists 2012-11-01
Series:Disease Models & Mechanisms
Online Access:http://dmm.biologists.org/content/5/6/823