ERK1 regulates the hematopoietic stem cell niches.

The mitogen-activated protein kinases (MAPK) ERK1 and ERK2 are among the major signal transduction molecules but little is known about their specific functions in vivo. ERK activity is provided by two isoforms, ERK1 and ERK2, which are ubiquitously expressed and share activators and substrates. Howe...

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Bibliographic Details
Main Authors: Nathalie Saulnier, Soizic Guihard, Xavier Holy, Elodie Decembre, Pierre Jurdic, Denis Clay, Vincent Feuillet, Gilles Pagès, Jacques Pouysségur, Françoise Porteu, Murielle Gaudry
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3268766?pdf=render