Recombinant human activated protein C in the treatment of acute respiratory distress syndrome: a randomized clinical trial.

Pulmonary coagulopathy may play a pathogenetic role in acute respiratory distress syndrome (ARDS), by contributing to alveolocapillary inflammation and increased permeability. Recombinant human activated protein C (rh-APC) may inhibit this process and thereby improve patient outcome.A prospective ra...

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Bibliographic Details
Main Authors: Alexander D Cornet, A B Johan Groeneveld, Jorrit J Hofstra, Alexander P Vlaar, Pieter R Tuinman, Arthur van Lingen, Marcel Levi, Armand R J Girbes, Marcus J Schultz, Albertus Beishuizen
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3954619?pdf=render