Downregulation of GNA15 Inhibits Cell Proliferation via P38 MAPK Pathway and Correlates with Prognosis of Adult Acute Myeloid Leukemia With Normal Karyotype

Downregulation of GNA15 Inhibits Cell Proliferation via P38 MAPK Pathway and Correlates with Prognosis of Adult Acute Myeloid Leukemia With Normal Karyotype

BackgroundThe prognosis of acute myeloid leukemia (AML) with a normal karyotype is highly heterogonous, and the current risk stratification is still insufficient to differentiate patients from high-risk to standard-risk. Changes in some genetic profiles may contribute to the poor prognosis of AML. A...

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Bibliographic Details
Main Authors: Mengya Li, Yu Liu, Yajun Liu, Lu Yang, Yan Xu, Weiqiong Wang, Zhongxing Jiang, Yanfang Liu, Shujuan Wang, Chong Wang
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-09-01
Series:Frontiers in Oncology
Subjects:
acute myeloid leukemia
GNA15
cell proliferation
P38 MAPK
prognosis
Online Access:https://www.frontiersin.org/articles/10.3389/fonc.2021.724435/full

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https://www.frontiersin.org/articles/10.3389/fonc.2021.724435/full

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