A realistic large-scale model of the cerebellum granular layer predicts circuit spatio-temporal filtering properties

The way the cerebellar granular layer transforms incoming mossy fiber signals into new spike patterns to be related to Purkinje cells is not yet clear. Here, a realistic computational model of the granular layer was developed and used to address four main functional hypotheses: center-surround organ...

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Bibliographic Details
Main Authors: Sergio Solinas, Thierry Nieus, Egidio D‘Angelo
Format: Article
Language:English
Published: Frontiers Media S.A. 2010-05-01
Series:Frontiers in Cellular Neuroscience
Subjects:
Online Access:http://journal.frontiersin.org/Journal/10.3389/fncel.2010.00012/full