Identification of amino acid residues that determine the substrate specificity of mammalian membrane-bound front-end fatty acid desaturases

Membrane-bound desaturases are physiologically and industrially important enzymes that are involved in the production of diverse fatty acids such as polyunsaturated fatty acids and their derivatives. Here, we identified amino acid residues that determine the substrate specificity of rat Δ6 desaturas...

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Bibliographic Details
Main Authors: Kenshi Watanabe, Makoto Ohno, Masahiro Taguchi, Seiji Kawamoto, Kazuhisa Ono, Tsunehiro Aki
Format: Article
Language:English
Published: Elsevier 2016-01-01
Series:Journal of Lipid Research
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S0022227520314048