Integrin α1 has a long helix, extending from the transmembrane region to the cytoplasmic tail in detergent micelles.

Integrin proteins are very important adhesion receptors that mediate cell-cell and cell-extracellular matrix interactions. They play essential roles in cell signaling and the regulation of cellular shape, motility, and the cell cycle. Here, the transmembrane and cytoplasmic (TMC) domains of integrin...

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Bibliographic Details
Main Authors: Chaohua Lai, Xiaoxi Liu, Changlin Tian, Fangming Wu
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/23646163/?tool=EBI