Dermal fibroblasts and triple-negative mammary epithelial cancer cells differentially stiffen their local matrix
The bulk measurement of extracellular matrix (ECM) stiffness is commonly used in mechanobiology. However, past studies by our group show that peri-cellular stiffness is quite heterogeneous and divergent from the bulk. We use optical tweezers active microrheology (AMR) to quantify how two phenotypica...
Main Authors: | , , |
---|---|
Format: | Article |
Language: | English |
Published: |
AIP Publishing LLC
2020-12-01
|
Series: | APL Bioengineering |
Online Access: | http://dx.doi.org/10.1063/5.0021030 |