Wnt-mediated repression via bipartite DNA recognition by TCF in the Drosophila hematopoietic system.
The Wnt/β-catenin signaling pathway plays many important roles in animal development, tissue homeostasis and human disease. Transcription factors of the TCF family mediate many Wnt transcriptional responses, promoting signal-dependent activation or repression of target gene expression. The mechanism...
Main Authors: | , , , |
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Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2014-08-01
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Series: | PLoS Genetics |
Online Access: | http://europepmc.org/articles/PMC4140642?pdf=render |