Wnt-mediated repression via bipartite DNA recognition by TCF in the Drosophila hematopoietic system.

The Wnt/β-catenin signaling pathway plays many important roles in animal development, tissue homeostasis and human disease. Transcription factors of the TCF family mediate many Wnt transcriptional responses, promoting signal-dependent activation or repression of target gene expression. The mechanism...

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Bibliographic Details
Main Authors: Chen U Zhang, Timothy A Blauwkamp, Peter E Burby, Ken M Cadigan
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-08-01
Series:PLoS Genetics
Online Access:http://europepmc.org/articles/PMC4140642?pdf=render