Phosphorylation of OGFOD1 by Cell Cycle-Dependent Kinase 7/9 Enhances the Transcriptional Activity of RNA Polymerase II in Breast Cancer Cells

2-oxoglutarate and iron-dependent oxygenase domain-containing protein 1 (OGFOD1) expression is upregulated in a variety of cancers and has been related to poor prognosis. However, despite this significance to cancer progression, the precise oncogenic mechanism of OGFOD1 is not understood. We demonst...

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Main Authors: Han-Teo Lee, Il-Hwan Lee, Jae-Hwan Kim, Sangho Lee, Sojung Kwak, Min-Young Suh, In-Young Hwang, Bu-Gyeong Kang, Sun-Shin Cha, Byung-Il Lee, Sang-Eun Lee, Jinmi Choi, Jae-Seok Roe, Eun-Jung Cho, Hong-Duk Youn
Format: Article
Language:English
Published: MDPI AG 2021-07-01
Series:Cancers
Subjects:
Online Access:https://www.mdpi.com/2072-6694/13/14/3418