Cellular Growth Arrest and Efflux Pumps Are Associated With Antibiotic Persisters in Streptococcus pyogenes Induced in Biofilm-Like Environments

Cellular Growth Arrest and Efflux Pumps Are Associated With Antibiotic Persisters in Streptococcus pyogenes Induced in Biofilm-Like Environments

Streptococcus pyogenes (group A Streptococcus-GAS) is an important pathogen for humans. GAS has been associated with severe and invasive diseases. Despite the fact that these bacteria remain universally susceptible to penicillin, therapeutic failures have been reported in some GAS infections. Many h...

Full description

Bibliographic Details
Main Authors: Caroline Lopes Martini, Amada Zambrana Coronado, Maria Celeste Nunes Melo, Clarice Neffa Gobbi, Úrsula Santos Lopez, Marcos Correa de Mattos, Thais Tavares Amorim, Ana Maria Nunes Botelho, Ana Tereza Ribeiro Vasconcelos, Luiz Gonzaga Paula Almeida, Paul J. Planet, Russolina Benedeta Zingali, Agnes Marie Sá Figueiredo, Bernadete Teixeira Ferreira-Carvalho
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-09-01
Series:Frontiers in Microbiology
Subjects:
Streptococcus pyogenes
drug refractory
persisters
efflux pump
antimicrobial resistance
clinical resistance
Online Access:https://www.frontiersin.org/articles/10.3389/fmicb.2021.716628/full

Internet

https://www.frontiersin.org/articles/10.3389/fmicb.2021.716628/full

Similar Items