Prospects of Indole derivatives as methyl transfer inhibitors: antimicrobial resistance managers

Prospects of Indole derivatives as methyl transfer inhibitors: antimicrobial resistance managers

Abstract Background It is prudent that novel classes of antibiotics be urgently developed to manage the WHO prioritized multi-drug resistant (MDR) pathogens posing an unprecedented medical crisis. Simultaneously, multiple essential proteins have to be targeted to prevent easy resistance development....

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Bibliographic Details
Main Authors: Suprim Tha, Sapana Shakya, Rajani Malla, Pramod Aryal
Format: Article
Language:English
Published: BMC 2020-05-01
Series:BMC Pharmacology and Toxicology
Subjects:
In silico drug design
Drug resistance
Indoles
SAM
Molecular docking
Online Access:http://link.springer.com/article/10.1186/s40360-020-00402-9

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http://link.springer.com/article/10.1186/s40360-020-00402-9

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