Yin Yang 1 sustains biosynthetic demands during brain development in a stage-specific manner

Yin Yang 1 sustains biosynthetic demands during brain development in a stage-specific manner

The transcription factor Yin Yang 1 (YY1) plays an important role in human disease, yet little is known about its role in brain development. This study shows that YY1 controls cerebral cortex development by maintaining proliferation and survival of neural progenitor cells via transcriptional regulat...

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Bibliographic Details
Main Authors: Luis Zurkirchen, Sandra Varum, Sonja Giger, Annika Klug, Jessica Häusel, Raphaël Bossart, Martina Zemke, Claudio Cantù, Zeynep Kalender Atak, Nicola Zamboni, Konrad Basler, Lukas Sommer
Format: Article
Language:English
Published: Nature Publishing Group 2019-05-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-019-09823-5

Internet

https://doi.org/10.1038/s41467-019-09823-5

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