Effects of corticosteroids vs halofuginone on vocal fold wound healing in an ovine model

Abstract Objectives To evaluate antifibrotic effects of corticosteroids and halofuginone, a small molecule inhibitor of Smad3, in an ovine model of vocal fold (VF) injury. Methods Thirty sheep, using a paired study design, underwent controlled right VF injury by biopsy and then were treated with eit...

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Bibliographic Details
Main Author: Jacqueline Allen
Format: Article
Language:English
Published: Wiley 2021-08-01
Series:Laryngoscope Investigative Otolaryngology
Subjects:
Online Access:https://doi.org/10.1002/lio2.602