Sex-Based Differences in Cardiac Gene Expression and Function in BDNF Val66Met Mice

Sex-Based Differences in Cardiac Gene Expression and Function in BDNF Val66Met Mice

Brain-derived neurotrophic factor (BDNF) is a pleiotropic neuronal growth and survival factor that is indispensable in the brain, as well as in multiple other tissues and organs, including the cardiovascular system. In approximately 30% of the general population, BDNF harbors a nonsynonymous single...

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Bibliographic Details
Main Authors: Marcus Negron, Jeffrey Kristensen, Van Thuan Nguyen, Lauren E. Gansereit, Frank J. Raucci, Julia L. Chariker, Aaron Heck, Imamulhaq Brula, Gabrielle Kitchen, Cassandra P. Awgulewitsch, Lin Zhong, Eric C. Rouchka, Simran Banga, Cristi L. Galindo
Format: Article
Language:English
Published: MDPI AG 2021-06-01
Series:International Journal of Molecular Sciences
Subjects:
brain-derived neurotrophic growth factor
dilated cardiomyopathy
rs6265 polymorphism
Duchenne muscular dystrophy
Val66Met
Online Access:https://www.mdpi.com/1422-0067/22/13/7002

Internet

https://www.mdpi.com/1422-0067/22/13/7002

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