Prevention of long-term memory loss after retrieval by an endogenous CaMKII inhibitor

Prevention of long-term memory loss after retrieval by an endogenous CaMKII inhibitor

Abstract CaMK2N1 and CaMK2N2 are endogenous inhibitors of calcium/calmodulin-dependent protein kinase II (CaMKII), a key synaptic signaling molecule for learning and memory. Here, we investigated the learning and memory function of CaMK2N1 by knocking-down its expression in dorsal hippocampus of mic...

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Bibliographic Details
Main Authors: Fabio Antonio Vigil, Keiko Mizuno, Walter Lucchesi, Victoria Valls-Comamala, Karl Peter Giese
Format: Article
Language:English
Published: Nature Publishing Group 2017-06-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-017-04355-8

Internet

https://doi.org/10.1038/s41598-017-04355-8

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