The Role of Complement Activating Collectins and Associated Serine Proteases in Patients With Hematological Malignancies, Receiving High-Dose Chemotherapy, and Autologous Hematopoietic Stem Cell Transplantations (Auto-HSCT)

The Role of Complement Activating Collectins and Associated Serine Proteases in Patients With Hematological Malignancies, Receiving High-Dose Chemotherapy, and Autologous Hematopoietic Stem Cell Transplantations (Auto-HSCT)

We conducted a prospective study of 312 patients (194 with multiple myeloma, 118 with lymphomas) receiving high-dose conditioning chemotherapy and autologous hematopoietic stem cell transplantation (auto-HSCT). Polymorphisms of MBL2 and MASP2 genes were investigated and serial measurements of serum...

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Main Authors: Anna S. Świerzko, Mateusz Michalski, Anna Sokołowska, Mateusz Nowicki, Łukasz Eppa, Agnieszka Szala-Poździej, Iwona Mitrus, Anna Szmigielska-Kapłon, Małgorzata Sobczyk-Kruszelnicka, Katarzyna Michalak, Aleksandra Gołos, Agnieszka Wierzbowska, Sebastian Giebel, Krzysztof Jamroziak, Marek L. Kowalski, Olga Brzezińska, Steffen Thiel, Jens C. Jensenius, Katarzyna Kasperkiewicz, Maciej Cedzyński
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-09-01
Series:Frontiers in Immunology
Subjects:
CL-LK
collectin
complement
hematopoietic stem cell transplantation (HSCT)
mannose-binding lectin (MBL)
MASP
Online Access:https://www.frontiersin.org/article/10.3389/fimmu.2018.02153/full

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https://www.frontiersin.org/article/10.3389/fimmu.2018.02153/full

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