Impairment of locomotor activity induced by the novel N-acylhydrazone derivatives LASSBio-785 and LASSBio-786 in mice

Impairment of locomotor activity induced by the novel N-acylhydrazone derivatives LASSBio-785 and LASSBio-786 in mice

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The N-acylhydrazone (NAH) analogues N-methyl 2-thienylidene 3,4-benzoylhydrazine (LASSBio-785) and N-benzyl 2-thienylidene 3,4-benzoylhydrazine (LASSBio-786) were prepared from 2-thienylidene 3,4-methylenedioxybenzoylhydrazine (LASSBio-294). The ability of LASSBio-785 and LASSBio...

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Bibliographic Details
Main Authors: G.A.P. Silva, A.E. Kummerle, F. Antunes, C.A.M. Fraga, E.J. Barreiro, G. Zapata-Sudo, R.T. Sudo
Format: Article
Language:English
Published: Associação Brasileira de Divulgação Científica 2013-03-01
Series:Brazilian Journal of Medical and Biological Research
Subjects:
N-acylhydrazone
Locomotor activity
Sedation
Hypnosis
Benzodiazepine receptor
Flumazenil
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2013000300263&lng=en&tlng=en

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http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2013000300263&lng=en&tlng=en

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