Combining motion analysis and microfluidics--a novel approach for detecting whole-animal responses to test substances.

Small, early life stages, such as zebrafish embryos are increasingly used to assess the biological effects of chemical compounds in vivo. However, behavioural screens of such organisms are challenging in terms of both data collection (culture techniques, drug delivery and imaging) and data evaluatio...

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Bibliographic Details
Main Authors: Tabitha S Rudin-Bitterli, Oliver Tills, John I Spicer, Phil F Culverhouse, Eric M Wielhouwer, Michael K Richardson, Simon D Rundle
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4251981?pdf=render