Nobiletin, a hexamethoxyflavonoid from citrus pomace, attenuates G1 cell cycle arrest and apoptosis in hypoxia-induced human trophoblast cells of JEG-3 and BeWo via regulating the p53 signaling pathway
Background: Hypoxia is associated with abnormal cell apoptosis in trophoblast cells, which causes fetal growth restriction and related placental pathologies. Few effective methods for the prevention and treatment of placenta-related diseases exist. Natural products and functional foods have always b...
Main Authors: | , , , , , , |
---|---|
Format: | Article |
Language: | English |
Published: |
Swedish Nutrition Foundation
2020-09-01
|
Series: | Food & Nutrition Research |
Subjects: | |
Online Access: | https://foodandnutritionresearch.net/index.php/fnr/article/view/5649/13909 |