PEIS: a novel approach of tumor purity estimation by identifying information sites through integrating signal based on DNA methylation data

Abstract Background Tumor purity plays an important role in understanding the pathogenic mechanism of tumors. The purity of tumor samples is highly sensitive to tumor heterogeneity. Due to Intratumoral heterogeneity of genetic and epigenetic data, it is suitable to study the purity of tumors. Among...

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Bibliographic Details
Main Authors: Shudong Wang, Lihua Wang, Yuanyuan Zhang, Shanchen Pang, Xinzeng Wang
Format: Article
Language:English
Published: BMC 2019-12-01
Series:BMC Bioinformatics
Subjects:
Online Access:https://doi.org/10.1186/s12859-019-3227-1