Comparative Utility of Genetic Determinants of Drug Resistance and Phenotypic Drug Susceptibility Profiling in Predicting Clinical Outcomes in Patients With Multidrug-Resistant Mycobacterium tuberculosis

Comparative Utility of Genetic Determinants of Drug Resistance and Phenotypic Drug Susceptibility Profiling in Predicting Clinical Outcomes in Patients With Multidrug-Resistant Mycobacterium tuberculosis

Setting: Programmatic management of drug-resistant tuberculosis in Ningbo, China.Objective: To assess whether data-driven genetic determinants of drug resistance patterns could outperform phenotypic drug susceptibility testing in predicting clinical meaningful outcomes among patients with multidrug-...

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Bibliographic Details
Main Authors: Yang Che, Tianchi Yang, Lv Lin, Yue Xiao, Feng Jiang, Yanfei Chen, Tong Chen, Jifang Zhou
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-04-01
Series:Frontiers in Public Health
Subjects:
genetic determinant
resistance
multidrug
mycobacterium tuberculosis
phenotypic drug susceptibility test
Online Access:https://www.frontiersin.org/articles/10.3389/fpubh.2021.663974/full

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https://www.frontiersin.org/articles/10.3389/fpubh.2021.663974/full

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