Proliferation of Highly Cytotoxic Human Natural Killer Cells by OX40L Armed NK-92 With Secretory Neoleukin-2/15 for Cancer Immunotherapy

Proliferation of Highly Cytotoxic Human Natural Killer Cells by OX40L Armed NK-92 With Secretory Neoleukin-2/15 for Cancer Immunotherapy

Adoptive natural killer (NK) cell transfer has been demonstrated to be a promising immunotherapy approach against malignancies, but requires the administration of sufficient activated cells for treatment effectiveness. However, the paucity of clinical-grade to support the for large-scale cell expans...

Full description

Bibliographic Details
Main Authors: Meng Guo, Chen Sun, Yuping Qian, Liye Zhu, Na Ta, Guangjian Wang, Jianming Zheng, Fengfu Guo, Yanfang Liu
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-04-01
Series:Frontiers in Oncology
Subjects:
neoleukin-2/15
OX40 ligand
cytotoxic activity
NK cell expansion
immunotherapy
Online Access:https://www.frontiersin.org/articles/10.3389/fonc.2021.632540/full

Internet

https://www.frontiersin.org/articles/10.3389/fonc.2021.632540/full

Similar Items