Andrographolide Suppresses the Growth and Metastasis of Luminal-Like Breast Cancer by Inhibiting the NF-κB/miR-21-5p/PDCD4 Signaling Pathway

Andrographolide Suppresses the Growth and Metastasis of Luminal-Like Breast Cancer by Inhibiting the NF-κB/miR-21-5p/PDCD4 Signaling Pathway

Tumor growth and metastasis are responsible for breast cancer-related mortality. Andrographolide (Andro) is a traditional anti-inflammatory drug used in the clinic that inhibits NF-κB activation. Recently, Andro has been found in the treatment of various cancers. Andro inhibits breast cell prolifera...

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Bibliographic Details
Main Authors: Junchen Li, Lixun Huang, Zinan He, Minggui Chen, Yi Ding, Yuying Yao, Youfa Duan, Li Zixuan, Cuiling Qi, Lingyun Zheng, Jiangchao Li, Rongxin Zhang, Xiaoming Li, Jianwei Dai, Lijing Wang, Qian-Qian Zhang
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-06-01
Series:Frontiers in Cell and Developmental Biology
Subjects:
luminal-like breast cancer
andrographolide
growth
metastasis
NF-κB/miR-21-5p/PDCD4 signaling pathway
Online Access:https://www.frontiersin.org/articles/10.3389/fcell.2021.643525/full

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https://www.frontiersin.org/articles/10.3389/fcell.2021.643525/full

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