Effect of adenovirus-mediated overexpression of PTEN on brain oxidative damage and neuroinflammation in a rat kindling model of epilepsy

Abstract. Background:. Epilepsy is a chronic and severe neurological disorder. Phosphatase and tensin homolog deleted on chromosome ten (PTEN)-deficient mice exhibit learning and memory deficits and spontaneous epilepsy. The aim of this study was to investigate the role of PTEN in brain oxidative da...

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Bibliographic Details
Main Authors: Zhi-Sheng Wu, Wen-Li Huang, Shu-Jie Gong, Yuan-Yuan Ji
Format: Article
Language:English
Published: Wolters Kluwer 2019-11-01
Series:Chinese Medical Journal
Online Access:http://journals.lww.com/10.1097/CM9.0000000000000496