Genomic Analysis of Localized High-Risk Prostate Cancer Circulating Tumor Cells at the Single-Cell Level

Genomic Analysis of Localized High-Risk Prostate Cancer Circulating Tumor Cells at the Single-Cell Level

Accurate risk classification of men with localized high-risk prostate cancer directly affects treatment management decisions and patient outcomes. A wide range of risk assessments and classifications are available. However, each one has significant limitations to distinguish between indolent and agg...

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Bibliographic Details
Main Authors: Aline Rangel-Pozzo, Songyan Liu, Gabriel Wajnberg, Xuemei Wang, Rodney J. Ouellette, Geoffrey G. Hicks, Darrel Drachenberg, Sabine Mai
Format: Article
Language:English
Published: MDPI AG 2020-08-01
Series:Cells
Subjects:
localized high-risk prostate cancer
circulating tumor cells
three-dimensional (3-D) telomere profiling
laser microdissection
whole-exome genome sequencing
somatic single nucleotide variants
Online Access:https://www.mdpi.com/2073-4409/9/8/1863

Internet

https://www.mdpi.com/2073-4409/9/8/1863

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