Impact of VKORC1, CYP4F2 and NQO1 gene variants on warfarin dose requirement in Han Chinese patients with catheter ablation for atrial fibrillation

Impact of VKORC1, CYP4F2 and NQO1 gene variants on warfarin dose requirement in Han Chinese patients with catheter ablation for atrial fibrillation

Abstract Background The anticoagulation of atrial fibrillation catheter ablation during the perioperative stage does matter and should be treated with discretion. We aimed to assess impact of three important genes participating in vitamin K cycle (i.e. VKORC1 rs9923231, CYP4F2 rs2108622 and NQO1 rs1...

Full description

Bibliographic Details
Main Authors: Jiao Li, Wenlong Yang, Zhonghui Xie, Kun Yu, Yuhua Chen, Kaijun Cui
Format: Article
Language:English
Published: BMC 2018-05-01
Series:BMC Cardiovascular Disorders
Subjects:
VKORC1
CYP4F2
NQO1
Catheter ablation
Atrial fibrillation
Warfarin
Online Access:http://link.springer.com/article/10.1186/s12872-018-0837-x

Internet

http://link.springer.com/article/10.1186/s12872-018-0837-x

Similar Items