Long-term modifications of epileptogenesis and hippocampal rhythms after prolonged hyperthermic seizures in the mouse

Complex febrile seizures are often reported in the history of patients with mesio-temporal lobe epilepsy (MTLE) but their role in its physiopathology remains controversial. We postulated that prolonged hyperthermic seizures might, as a “single-hit”, modify the hippocampal rhythms, facilitate epilept...

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Bibliographic Details
Main Authors: Sophie Hamelin, Benoit Pouyatos, Reham Khalaf-Nazzal, Tanguy Chabrol, Fiona Francis, Olivier David, Antoine Depaulis
Format: Article
Language:English
Published: Elsevier 2014-09-01
Series:Neurobiology of Disease
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S0969996114001430