Exploration of multi-state conformational dynamics and underlying global functional landscape of maltose binding protein.

An increasing number of biological machines have been revealed to have more than two macroscopic states. Quantifying the underlying multiple-basin functional landscape is essential for understanding their functions. However, the present models seem to be insufficient to describe such multiple-state...

Full description

Bibliographic Details
Main Authors: Yong Wang, Chun Tang, Erkang Wang, Jin Wang
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS Computational Biology
Online Access:http://europepmc.org/articles/PMC3330084?pdf=render