Empirical models for anatomical and physiological changes in a human mother and fetus during pregnancy and gestation.

Many parameters treated as constants in traditional physiologically based pharmacokinetic models must be formulated as time-varying quantities when modeling pregnancy and gestation due to the dramatic physiological and anatomical changes that occur during this period. While several collections of em...

Full description

Bibliographic Details
Main Authors: Dustin F Kapraun, John F Wambaugh, R Woodrow Setzer, Richard S Judson
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2019-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0215906