The glycosylphosphatidylinositol-PLC in Trypanosoma brucei forms a linear array on the exterior of the flagellar membrane before and after activation.

The glycosylphosphatidylinositol-PLC in Trypanosoma brucei forms a linear array on the exterior of the flagellar membrane before and after activation.

Bloodstream forms of Trypanosoma brucei contain a glycosylphosphatidylinositol-specific phospholipase C (GPI-PLC) that cleaves the GPI-anchor of the variable surface glycoprotein (VSG). Its location in trypanosomes has been controversial. Here, using confocal microscopy and surface labelling techniq...

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Bibliographic Details
Main Authors: Orla Hanrahan, Helena Webb, Robert O'Byrne, Elaine Brabazon, Achim Treumann, Jack D Sunter, Mark Carrington, H Paul Voorheis
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2009-06-01
Series:PLoS Pathogens
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/19503825/?tool=EBI

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/19503825/?tool=EBI

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