Single-Cell Transcriptome Analysis of CD34+ Stem Cell-Derived Myeloid Cells Infected With Human Cytomegalovirus

Single-Cell Transcriptome Analysis of CD34+ Stem Cell-Derived Myeloid Cells Infected With Human Cytomegalovirus

Myeloid cells are important sites of lytic and latent infection by human cytomegalovirus (CMV). We previously showed that only a small subset of myeloid cells differentiated from CD34+ hematopoietic stem cells is permissive to CMV replication, underscoring the heterogeneous nature of these populatio...

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Bibliographic Details
Main Authors: Melissa Galinato, Kristen Shimoda, Alexis Aguiar, Fiona Hennig, Dario Boffelli, Michael A. McVoy, Laura Hertel
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-03-01
Series:Frontiers in Microbiology
Subjects:
single-cell
tropism
cytomegalovirus
myeloid
10× genomics
RNAseq
Online Access:https://www.frontiersin.org/article/10.3389/fmicb.2019.00577/full

Internet

https://www.frontiersin.org/article/10.3389/fmicb.2019.00577/full

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