Orphan receptor GPR158 controls stress-induced depression

Orphan receptor GPR158 controls stress-induced depression

Stress can be a motivational force for decisive action and adapting to novel environment; whereas, exposure to chronic stress contributes to the development of depression and anxiety. However, the molecular mechanisms underlying stress-responsive behaviors are not fully understood. Here, we identifi...

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Bibliographic Details
Main Authors: Laurie P Sutton, Cesare Orlandi, Chenghui Song, Won Chan Oh, Brian S Muntean, Keqiang Xie, Alice Filippini, Xiangyang Xie, Rachel Satterfield, Jazmine D W Yaeger, Kenneth J Renner, Samuel M Young Jr, Baoji Xu, Hyungbae Kwon, Kirill A Martemyanov
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2018-02-01
Series:eLife
Subjects:
orphan receptors
depression
GPCR signaling
stress
Online Access:https://elifesciences.org/articles/33273

Internet

https://elifesciences.org/articles/33273

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