Research Progress on the Mechanism and Clinical Data of Cereblon 
in Reversing the Resistance of Lung Cancer to PD-1 Antibody by T cells

Research Progress on the Mechanism and Clinical Data of Cereblon 
in Reversing the Resistance of Lung Cancer to PD-1 Antibody by T cells

Programmed cell death receptor 1 (PD-1) is a membrance-spanning protein mostly expressed in the T cell, and combines with programmed cell death ligand 1 (PD-L1) in the targeting cell. When binding to the ligand on tumor cells, PD-1 as an immunosuppressive molecule, can inhibit the immune function of...

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Bibliographic Details
Main Authors: Jingjing GUO, Di MU, Ying HAN
Format: Article
Language:zho
Published: Chinese Anti-Cancer Association; Chinese Antituberculosis Association 2021-01-01
Series:Chinese Journal of Lung Cancer
Subjects:
cereblon
t cell
programmed cell death receptor 1 antibody
lung neoplasms
Online Access:http://dx.doi.org/10.3779/j.issn.1009-3419.2020.102.49

Internet

http://dx.doi.org/10.3779/j.issn.1009-3419.2020.102.49

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