Parallel profiling of immune infiltrate subsets in uveal melanoma versus cutaneous melanoma unveils similarities and differences: A pilot study

Parallel profiling of immune infiltrate subsets in uveal melanoma versus cutaneous melanoma unveils similarities and differences: A pilot study

The low response rates to immunotherapy in uveal melanoma (UM) sharply contrast with reputable response rates in cutaneous melanoma (CM) patients. To characterize the mechanisms responsible for resistance to immunotherapy in UM, we performed immune profiling in tumors from 10 metastatic UM patients...

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Bibliographic Details
Main Authors: Yong Qin, Mariana Petaccia de Macedo, Alexandre Reuben, Marie-Andrée Forget, Cara Haymaker, Chantale Bernatchez, Christine N. Spencer, Vancheswaran Gopalakrishnan, Sujan Reddy, Zachary A. Cooper, Orenthial J. Fulbright, Renjith Ramachandran, Arely Wahl, Esteban Flores, Shawne T. Thorsen, Rene J. Tavera, Claudius Conrad, Michelle D. Williams, Michael T. Tetzlaff, Wei-Lien Wang, Dan S. Gombos, Bita Esmaeli, Rodabe N. Amaria, Patrick Hwu, Jennifer A. Wargo, Alexander J. Lazar, Sapna P. Patel
Format: Article
Language:English
Published: Taylor & Francis Group 2017-06-01
Series:OncoImmunology
Subjects:
cutaneous melanoma
immune profile
tumor infiltrating lymphocytes
uveal melanoma
Online Access:http://dx.doi.org/10.1080/2162402X.2017.1321187

Internet

http://dx.doi.org/10.1080/2162402X.2017.1321187

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