Plectin-1 targeted AAV vector for the molecular imaging of pancreatic cancer

Pancreatic ductal adenocarcinoma (PDAC) is highly malignant disease that is the 4th leading cause of cancer-related death in the US. Gene therapy using AAV vectors to selectively deliver genes to PDAC cells is an attractive treatment option for pancreatic cancer. However, most AAV serotypes display...

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Bibliographic Details
Main Authors: Prasad R. Konkalmatt, Defeng eDeng, Stephanie eThomas, Michael T. Wu, Craig D. Logsdon, Brent A. French, Kimberly A Kelly
Format: Article
Language:English
Published: Frontiers Media S.A. 2013-04-01
Series:Frontiers in Oncology
Subjects:
aav
Online Access:http://journal.frontiersin.org/Journal/10.3389/fonc.2013.00084/full