Functional evidence of distinct electrophile-induced activation states of the ion channel TRPA1
Transient Receptor Potential Ankyrin 1 (TRPA1) is a tetrameric, nonselective cation channel expressed on nociceptive sensory nerves whose activation elicits nocifensive responses (e.g. pain). TRPA1 is activated by electrophiles found in foods and pollution, or produced during inflammation and oxidat...
Main Authors: | , , |
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Format: | Article |
Language: | English |
Published: |
Elsevier
2021-09-01
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Series: | Biochemistry and Biophysics Reports |
Subjects: | |
Online Access: | http://www.sciencedirect.com/science/article/pii/S2405580821001382 |