Changes to the cervicovaginal microbiota and cervical cytokine profile following surgery for cervical intraepithelial neoplasia

Abstract Persistent HPV infection associated with immune modulation may result in high-grade squamous intraepithelial lesions (CIN)2/3. Currently, there is little information on the cervicovaginal microbiome, local cytokine levels and HPV infection related to CIN. Follow-up of patients after local s...

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Bibliographic Details
Main Authors: Rina Kawahara, Takuma Fujii, Iwao Kukimoto, Hiroyuki Nomura, Rie Kawasaki, Eiji Nishio, Ryoko Ichikawa, Tetsuya Tsukamoto, Aya Iwata
Format: Article
Language:English
Published: Nature Publishing Group 2021-01-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-020-80176-6