Acteoside and Isoacteoside Protect Amyloid β Peptide Induced Cytotoxicity, Cognitive Deficit and Neurochemical Disturbances In Vitro and In Vivo

Acteoside and Isoacteoside Protect Amyloid β Peptide Induced Cytotoxicity, Cognitive Deficit and Neurochemical Disturbances In Vitro and In Vivo

Acteoside and isoacteoside, two phenylethanoid glycosides, coexist in some plants. This study investigates the memory-improving and cytoprotective effects of acteoside and isoacteoside in amyloid β peptide 1-42 (Aβ 1-42)-infused rats and Aβ 1-42-treated SH-SY5Y cells. It further elucidates the role...

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Bibliographic Details
Main Authors: Young-Ji Shiao, Muh-Hwan Su, Hang-Ching Lin, Chi-Rei Wu
Format: Article
Language:English
Published: MDPI AG 2017-04-01
Series:International Journal of Molecular Sciences
Subjects:
acteoside
isoacetoside
amyloid β peptide
Morris water maze
acetylcholine
amyloid cascade
Online Access:http://www.mdpi.com/1422-0067/18/4/895

Internet

http://www.mdpi.com/1422-0067/18/4/895

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